The phased array feeds (PAFs) receiver is a next-generation microwave receiver that provides a new solution to reduce Radio Frequency Interference (RFI) for large-aperture radio astronomy telescopes. The PAFs receiver samples the electromagnetic wave in the focal plane of the radio telescope in spatial domain and returns the time-domain array signal. The use of Minimum Variance Distortionless Response (MVDR) beamformer allows for adaptive identification of the orientation of RFI while suppressing the power of RFI in the output signal, thereby enhancing the sensitivity of the radio telescope. The simulation results show that the MVDR beamformer has a strong ability to identify and mitigate active high-energy radio interference. Meanwhile, the beamformer has a strong ability to mitigate passive interference caused by the accumulation of additive noise in each array element channel. Therefore, the MVDR beamformer for PAFs receiver enhances the anti-interference capability of the radio telescope in the increasingly complex electromagnetic wave environment.